AMBERLITE XAD-16 is a nonionic, hydrophobic, cross-linked polymeric adsorbent supplied as insoluble white beads. It is characterized by its macroreticular structure, which provides both a continuous polymer phase and a continuous pore phase, offering high surface area and porosity . This adsorbent is specifically designed to capture hydrophobic molecules from polar solvents and volatile organic compounds from vapor streams . It is ideal for use in column or batch operations and is effective for the adsorption of organic substances with relatively low to medium molecular weight . The product is widely utilized in applications such as the purification of antibiotics, recovery of water-soluble steroids, amino acids, and proteins, as well as the removal of nonpolar compounds from polar solvents .